Mylene Huebecker

Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson’s disease

Mylene Huebecker, Elizabeth B. Moloney, Aarnoud C. van der Spoel et al. · Molecular Neurodegeneration · 2019 · 171 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Fetal gene therapy for neurodegenerative disease of infants

Giulia Massaro, Citra Nurfarah Zaini Mattar, Andrew M.S. Wong et al. · Nature Medicine · 2018 · 166 citations

Medicine, Neuroscience, Pediatrics +14

Amyotrophic lateral sclerosis and denervation alter sphingolipids and up-regulate glucosylceramide synthase

Alexandre Henriques, Vincent Croixmarie, David A. Priestman et al. · Human Molecular Genetics · 2015 · 94 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain

Penelope J. Hallett, Mylene Huebecker, Oeystein Roed Brekk et al. · Neurobiology of Aging · 2018 · 88 citations · Full text

Life Sciences, Genetics, Neuroscience +17

AAV9 intracerebroventricular gene therapy improves lifespan, locomotor function and pathology in a mouse model of Niemann–Pick type C1 disease

Michael P. Hughes, Dave A. Smith, Lauren Morris et al. · Human Molecular Genetics · 2018 · 72 citations · Full text

Life Sciences, Neurology, Neuroscience +17