Aimee L. Eggler

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

Aimee L. Eggler, Guowen Liu, John M. Pezzuto et al. · Proceedings of the National Academy of Sciences · 2005 · 447 citations · Full text

Modification of Keap1 Cysteine Residues by Sulforaphane

Chenqi Hu, Aimee L. Eggler, Andrew D. Mesecar et al. · Chemical Research in Toxicology · 2011 · 285 citations

Reductive Stress, Bioorganic Chemistry, Aldo-keto Reductase +14

Xanthohumol Isolated from <i>Humulus lupulus</i> Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase

Birgit M. Dietz, Young-Hwa Kang, Guowen Liu et al. · Chemical Research in Toxicology · 2005 · 204 citations · Full text

Phytoalexin, Quinone Oxidoreductase, Biosynthesis +13

Discovery, Synthesis, And Structure-Based Optimization of a Series of <i>N</i>-(<i>tert</i>-Butyl)-2-(<i>N</i>-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease

Jon Jacobs, Valerie Grum‐Tokars, Ya Zhou et al. · Journal of Medicinal Chemistry · 2012 · 202 citations · Full text

Molecular Docking, Medicinal Chemistry, Biochemistry +15

Sites of alkylation of human Keap1 by natural chemoprevention agents

Yan Luo, Aimee L. Eggler, Dongting Liu et al. · Journal of the American Society for Mass Spectrometry · 2007 · 181 citations · Full text

Reductive Stress, Signal Transduction, Chemoprevention Strategy +15