Eduardo L. Setti

Design and Synthesis of Tri-Ring P₃ Benzamide-Containing Aminonitriles as Potent, Selective, Orally Effective Inhibitors of Cathepsin K

James T. Palmer, Clifford Bryant, Dan-Xiong Wang et al. · Journal of Medicinal Chemistry · 2005 · 94 citations · Full text

Pharmaceutical Science, Sclerostin, Bone Resorption +18

A Novel Class of Nonpeptidic Biaryl Inhibitors of Human Cathepsin K

Joël Robichaud, Renata M. Oballa, Peppi Prasit et al. · Journal of Medicinal Chemistry · 2003 · 82 citations · Full text

Sclerostin, Bioorganic Chemistry, Human Cathepsin K +18

Identification of 1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea Hydrochloride (CEP-32496), a Highly Potent and Orally Efficacious Inhibitor of V-RAF Murine Sarcoma Viral Oncogene Homologue B1 (BRAF) V600E

Martin W. Rowbottom, Raffaella Faraoni, Qi Chao et al. · Journal of Medicinal Chemistry · 2011 · 58 citations · Full text

Orally Efficacious Inhibitor, Chemoprevention Strategy, Immunology +19

3,4-Disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P2 elements for selectivity

Eduardo L. Setti, Dana Davis, Tobee Chung et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 56 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +9

β-Substituted Cyclohexanecarboxamide:  A Nonpeptidic Framework for the Design of Potent Inhibitors of Cathepsin K

Sheldon N. Crane, W. Cameron Black, James T. Palmer et al. · Journal of Medicinal Chemistry · 2006 · 36 citations · Full text