Raffaella Faraoni

A quantitative analysis of kinase inhibitor selectivity

Mazen W. Karaman, Sanna Herrgård, Daniel K. Treiber et al. · Nature Biotechnology · 2008 · 2.4K citations

Drug Target, Signal Transduction, Medicine +6

A Catalytic Asymmetric Three‐Component 1,4‐Addition/Aldol Reaction: Enantioselective Synthesis of the Spirocyclic System of Vannusal A

K. C. Nicolaou, Wenjun Tang, Philippe Dagneau et al. · Angewandte Chemie International Edition · 2005 · 105 citations

Natural Product Synthesis, Engineering, Natural Sciences +13

Total Synthesis and Structural Revision of Vannusals A and B: Synthesis of the Originally Assigned Structure of Vannusal B

K. C. Nicolaou, Adrian Ortiz, Hongjun Zhang et al. · Journal of the American Chemical Society · 2010 · 65 citations · Full text

Identification of 1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea Hydrochloride (CEP-32496), a Highly Potent and Orally Efficacious Inhibitor of V-RAF Murine Sarcoma Viral Oncogene Homologue B1 (BRAF) V600E

Martin W. Rowbottom, Raffaella Faraoni, Qi Chao et al. · Journal of Medicinal Chemistry · 2011 · 58 citations · Full text

Orally Efficacious Inhibitor, Chemoprevention Strategy, Immunology +19

CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and <i>In Vivo</i> Antitumor Activity

Joyce James, Bruce Ruggeri, Robert C. Armstrong et al. · Molecular Cancer Therapeutics · 2012 · 47 citations · Full text

Tumor Biology, Active Braf Inhibitor, Novel Therapy +15