Graham Lunn

Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain

Mark D. Andrews, Kerry af Forselles, Kevin Beaumont et al. · ACS Medicinal Chemistry Letters · 2015 · 80 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion

G. Stuart Cockerill, Richard Angell, Alexandre F. Bedernjak et al. · Journal of Medicinal Chemistry · 2021 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Investigation of the effect of molecular properties on the binding kinetics of a ligand to its biological target

Duncan C. Miller, Graham Lunn, Peter Jones et al. · MedChemComm · 2012 · 51 citations

Natural Sciences, Biochemistry, Chemistry +17

Discovery and synthesis of a new class of opioid ligand having a 3-azabicyclo[3.1.0]hexane core. An example of a ‘magic methyl’ giving a 35-fold improvement in binding

Graham Lunn, B. J. BANKS, Robert Crook et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 31 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +14

SAR and biological evaluation of 3-azabicyclo[3.1.0]hexane derivatives as μ opioid ligands

Graham Lunn, Lee R. Roberts, Stéphane Content et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 10 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14