Kurt van Vloten

Design, synthesis and selection of DNA-encoded small-molecule libraries

Matthew Clark, Raksha Acharya, Christopher C. Arico-Muendel et al. · Nature Chemical Biology · 2009 · 691 citations · Full text

Pharmacy, Biotechnology, Medicinal Chemistry +12

Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT)

Hongfeng Deng, Heather P. O’Keefe, Christopher P. Davie et al. · Journal of Medicinal Chemistry · 2012 · 149 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Discovery of biaryl carboxylamides as potent RORγ inverse agonists

Jianhua Chao, Istvan Enyedy, Kurt van Vloten et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Discovery of novel pyrazole-containing benzamides as potent RORγ inverse agonists

Tao Wang, Daliya Banerjee, Tonika Bohnert et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 35 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Synthesis of [1,2,4]triazolo[1,5-a]pyrazines as adenosine A2A receptor antagonists

James J. Dowling, Jeffrey T. Vessels, Serajul Haque et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8