Concepedia

P. Yakowec

PY

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Publications

14

Citations

1.4K

H-Index

13

Active since

1996

Affiliations

Amgen (United States)(Current)

P. Yakowec is an author at Amgen (United States) specializing in drug discovery, pharmacology, and pharmacy.

Publications per year

1996–2014

14

Publications

14

Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development

Daqing Sun, Zhihong Li, Yosup Rew et al. · Journal of Medicinal Chemistry · 2014 · 296 citations · Full text

, , +7

14-3-3 Proteins Act as Negative Regulators of the Mitotic Inducer Cdc25 in<i>Xenopus</i>Egg Extracts

Akiko Kumagai, P. Yakowec, William G. Dunphy · Molecular Biology of the Cell · 1998 · 212 citations · Full text

, , +17

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Yosup Rew, Daqing Sun, Felix González-López de Turiso et al. · Journal of Medicinal Chemistry · 2012 · 169 citations · Full text

, , +14

Discovery and Optimization of Chromenotriazolopyrimidines as Potent Inhibitors of the Mouse Double Minute 2−Tumor Protein 53 Protein−Protein Interaction

John G. Allen, Matthew P. Bourbeau, G. Erich Wohlhieter et al. · Journal of Medicinal Chemistry · 2009 · 147 citations · Full text

, , +13

Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors

Noel D. D’Angelo, Tae‐Seong Kim, Kristin L. Andrews et al. · Journal of Medicinal Chemistry · 2011 · 119 citations · Full text

, , +14

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