Cymbelene Nardo

Development of an automated mass spectrometry system for the quantitative analysis of liver microsomal incubation samples: a tool for rapid screening of new compounds for metabolic stability

Walter A. Korfmacher, Cynthia A. Palmer, Cymbelene Nardo et al. · Rapid Communications in Mass Spectrometry · 1999 · 80 citations

Antitumor 8-chlorobenzocycloheptapyridines: a new class of selective, nonpeptidic, nonsulfhydryl inhibitors of ras farnesylation

Alan K. Mallams, F. George Njoroge, Ronald J. Doll et al. · Bioorganic & Medicinal Chemistry · 1997 · 43 citations

Medicinal Chemistry, Engineering, Medicine +11

Pharmacokinetic screening for the selection of new drug discovery candidates is greatly enhanced through the use of liquid chromatography–atmospheric pressure ionization tandem mass spectrometry

Matthew Bryant, Walter A. Korfmacher, Shiyong Wang et al. · Journal of Chromatography A · 1997 · 42 citations

Biochemistry, Gas Chromatography, Medicine +11

Inhibitors of Farnesyl Protein Transferase. 4-Amido, 4-Carbamoyl, and 4-Carboxamido Derivatives of 1-(8-Chloro-6,11-dihydro-5<i>H</i>-benzo[5,6]- cyclohepta[1,2-<i>b</i>]pyridin-11-yl)piperazine and 1-(3-Bromo-8-chloro-6,11- dihydro-5<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]pyridin-11-yl)piperazine

Alan K. Mallams, Randall R. Rossman, Ronald J. Doll et al. · Journal of Medicinal Chemistry · 1998 · 28 citations · Full text

Bioorganic Chemistry, Organic Chemistry, 4-Carboxamido Derivatives +18

Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists

Michael Berlin, Pauline C. Ting, Wayne Vaccaro et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 16 citations · Full text

Biochemistry, Cyp450 Inhibition, Medicine +5