Alan K. Mallams

Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.

Ming Liu, Matthew Bryant, Jianping Chen et al. · PubMed · 1998 · 309 citations

Sch 66336, Chemoprevention Strategy, Farnesyl Protein Transferase +15

SCH529074, a Small Molecule Activator of Mutant p53, Which Binds p53 DNA Binding Domain (DBD), Restores Growth-suppressive Function to Mutant p53 and Interrupts HDM2-mediated Ubiquitination of Wild Type p53

Mark J. Demma, Eugene Maxwell, Robert Ramos et al. · Journal of Biological Chemistry · 2010 · 106 citations · Full text

(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]- pyridin-11(<i>R</i>)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336):  A Very Potent Farnesyl Protein Transferase Inhibitor as a Novel Antitumor Agent

F. George Njoroge, Arthur G. Taveras, Joseph Kelly et al. · Journal of Medicinal Chemistry · 1998 · 97 citations · Full text

Bioorganic Chemistry, Pharmacotherapy, Pharmaceutical Chemistry +18

Optical rotatory dispersion of carotenoids

L. Bartlett, W. Klyne, W. P. Mose et al. · Journal of the Chemical Society C Organic · 1969 · 93 citations

Carotenoid, Engineering, Photochemistry +12

Tricyclic Farnesyl Protein Transferase Inhibitors:  Crystallographic and Calorimetric Studies of Structure−Activity Relationships

Corey L. Strickland, Patricia C Weber, William T. Windsor et al. · Journal of Medicinal Chemistry · 1999 · 88 citations · Full text

Amide Carbonyl, Molecular Biology, Complex Formation +17