Seth H. Cassel

Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes

Nazar Mashtalir, Brittany C. Michel, Jie Luo et al. · Cell · 2018 · 749 citations · Full text

Chromatin, Modular Organization, Chromatin Structure +9

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair

Joseph R. Klim, Luis A. Williams, Francesco Limone et al. · Nature Neuroscience · 2019 · 638 citations · Full text

Als-implicated Protein Tdp-43, Neurodegenerative Diseases, Neuroregeneration +10

A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation

Brittany C. Michel, Seth H. Cassel, Nazar Mashtalir et al. · Nature Cell Biology · 2018 · 417 citations

Non-canonical Swi/snf Complex, Oncogenic Agent, Medicine +9

SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters

Robert Nakayama, John L. Pulice, Alfredo M. Valencia et al. · Nature Genetics · 2017 · 283 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +12

Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens

Joshua Pan, Robin M. Meyers, Brittany C. Michel et al. · Cell Systems · 2018 · 168 citations · Full text