Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes

Nazar Mashtalir, Brittany C. Michel, Jie Luo, +11

Cell

ChromatinModular OrganizationChromatin StructureChromatin RemodelingNatural Sciences +7

A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation

Brittany C. Michel, Seth H. Cassel, Nazar Mashtalir, +15

Nature Cell Biology

Non-canonical Swi/snf ComplexOncogenic AgentMedicineSynthetic Lethal TargetCancer Genomics +7

The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression

Helen Yu, Nazar Mashtalir, Salima Daou, +9

Molecular and Cellular Biology

GeneticsMolecular BiologyCell ProliferationMolecular GeneticsTernary Complex +19

The Leptin-Deficient (<i>ob/ob</i>) Mouse

Viktor R. Drel, Nazar Mashtalir, Olga Ilnytska, +4

Diabetes

Peripheral NerveAdipokinesSynaptic SignalingInsulin SignalingMetabolic Syndrome +18

High-Fat Diet–Induced Neuropathy of Pre-Diabetes and Obesity

Irina G. Obrosova, Olga Ilnytska, Valeriy V. Lyzogubov, +4

Diabetes

Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O

Nazar Mashtalir, Salima Daou, Haithem Barbour, +6

Molecular Cell

Signaling PathwayCell RegulationMedicineCytoplasmic Sequestration MediatedTumor Suppressor Bap1 +6

A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms

Nazar Mashtalir, Hiroshi Suzuki, Daniel P. Farrell, +13

Cell

Signal TransductionDisease MechanismDisease EtiologyPathogenesisHumoral Response +7

Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens

Joshua Pan, Robin M. Meyers, Brittany C. Michel, +10

Cell Systems

Chromatin landscape signals differentially dictate the activities of mSWI/SNF family complexes

Nazar Mashtalir, Hai T. Dao, Akshay Sankar, +9

Science

Poly(ADP-Ribose) Polymerase Inhibition Alleviates Experimental Diabetic Sensory Neuropathy

Olga Ilnytska, Valeriy V. Lyzogubov, Martin Stevens, +5

Diabetes

Parp InhibitorPain MedicineNeuropathic PainMolecular PainBiomedical Engineering +15