Helen Yu

Clinical targeting of HIV capsid protein with a long-acting small molecule

John O. Link, Martin S. Rhee, Winston C. Tse et al. · Nature · 2020 · 421 citations · Full text

Pharmacy, Molecular Biology, Pharmaceutics +12

Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair

Helen Yu, Helen Pak, Ian Hammond-Martel et al. · Proceedings of the National Academy of Sciences · 2013 · 388 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

Manuel Tsiang, G.S. Jones, Joshua Goldsmith et al. · Antimicrobial Agents and Chemotherapy · 2016 · 283 citations · Full text

Life Sciences, Pharmacology, Pharmacotherapy +17

Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing

Datsen G. Wei, Vicki Chiang, Elizabeth Fyne et al. · PLoS Pathogens · 2014 · 281 citations · Full text

Medicine, Immunology, Pharmacology +17

The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression

Helen Yu, Nazar Mashtalir, Salima Daou et al. · Molecular and Cellular Biology · 2010 · 269 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14