Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains

Carmine Carpenito, Michael C. Milone, Raffit Hassan, +11

Proceedings of the National Academy of Sciences

Engineering Artificial Antigen-presenting Cells to Express a Diverse Array of Co-stimulatory Molecules

Megan M. Suhoski, Tatiana N. Golovina, Nicole A. Aqui, +6

Molecular Therapy

The Inducible Costimulator (ICOS) Is Critical for the Development of Human T _H 17 Cells

Chrystal M. Paulos, Carmine Carpenito, Gabriela Plesa, +6

Science Translational Medicine

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

Angel Varela‐Rohena, Peter Molloy, Steven M. Dunn, +16

Nature Medicine

Hiv-1 Immune EscapeAutoimmune DiseaseCd8 T CellsT-regulatory CellHuman Retrovirus +9

4-1BB Is Superior to CD28 Costimulation for Generating CD8+ Cytotoxic Lymphocytes for Adoptive Immunotherapy

Hua Zhang, Kristen Snyder, Megan M. Suhoski, +4

The Journal of Immunology

CD28 Costimulation Is Essential for Human T Regulatory Expansion and Function

Tatiana N. Golovina, Tatiana Mikheeva, Megan M. Suhoski, +12

The Journal of Immunology

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

Keli L. Hippen, Paul Harker‐Murray, Stephen B. Porter, +14

Blood

Cdc42-interacting protein–4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse

Pinaki P. Banerjee, Rahul Pandey, Rena Zheng, +3

The Journal of Experimental Medicine

Mtoc PolarizationProtein FunctionSignal TransductionMedicineCell Trafficking +13

IL-21 promotes the expansion of CD27+CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells

Saskia J. Santegoets, Annelies W. Turksma, Megan M. Suhoski, +9

Journal of Translational Medicine

Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines

Ilkka Junttila, Rémi J. Creusot, Ignacio Moraga, +11

Nature Chemical Biology

InflammationCytokineEngineered Interleukin-4 SuperkinesImmunologyAutoimmunity +4