Gabriela Plesa

A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma

Donald M. O’Rourke, MacLean P. Nasrallah, Arati Desai et al. · Science Translational Medicine · 2017 · 1.7K citations · Full text

Cell Therapy, Antigen Loss, Immunology +16

CRISPR-engineered T cells in patients with refractory cancer

Edward A. Stadtmauer, Joseph A. Fraietta, Megan M. Davis et al. · Science · 2020 · 1.4K citations · Full text

Gene Editing of <i>CCR5</i> in Autologous CD4 T Cells of Persons Infected with HIV

Pablo Tebas, David Stein, Winson W. Tang et al. · New England Journal of Medicine · 2014 · 1.3K citations · Full text

Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies

Gregory L. Beatty, Andrew R. Haas, Marcela V. Maus et al. · Cancer Immunology Research · 2013 · 847 citations · Full text

Off-target Toxicity, T-regulatory Cell, Immunology +16

B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma

Adam D. Cohen, Alfred L. Garfall, Edward A. Stadtmauer et al. · Journal of Clinical Investigation · 2019 · 768 citations · Full text