Daniel D. Holsworth

A Novel Tankyrase Small-Molecule Inhibitor Suppresses <i>APC</i> Mutation–Driven Colorectal Tumor Growth

Ted Lau, Emily Chan, Marinella Callow et al. · Cancer Research · 2013 · 320 citations

Medicine, Oncology, Pharmacology +17

Structural Basis and SAR for G007-LK, a Lead Stage 1,2,4-Triazole Based Specific Tankyrase 1/2 Inhibitor

A. E. Voronkov, Daniel D. Holsworth, Jo Waaler et al. · Journal of Medicinal Chemistry · 2013 · 123 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Steric Hindrance as a Basis for Structure-Based Design of Selective Inhibitors of Protein-Tyrosine Phosphatases

Lars Iversen, Henrik Sune Andersen, Karin Möller et al. · Biochemistry · 2001 · 74 citations

Life Sciences, Biochemistry, Pharmacology +17

Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors

Noel A. Powell, Fred L. Ciske, Cuiman Cai et al. · Bioorganic & Medicinal Chemistry · 2007 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Vinyl isocyanates in synthesis. [4 + 2] Cycloaddition reactions with benzyne addends

James H. Rigby, Daniel D. Holsworth, K. James · The Journal of Organic Chemistry · 1989 · 47 citations

Natural Sciences, Chemistry, Analytical Chemistry +10