Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine

Cindy L. Moran, Vi-Huyen Le, Krishna C. Chimalakonda, +16

Analytical Chemistry

Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors

Noel A. Powell, Fred L. Ciske, Cuiman Cai, +16

Bioorganic & Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryRational DesignNatural SciencesMedicine +4

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases

Mark E. Schnute, David Anderson, Roger J. Brideau, +17

Bioorganic & Medicinal Chemistry Letters

MedicineAntiviral TherapyMolecular BiologyVirologyHuman Herpesvirus Polymerases +4

Binding thermodynamics of substituted diaminopyrimidine renin inhibitors

Ronald W. Sarver, Jeanette Peevers, Wayne L. Cody, +14

Analytical Biochemistry

BiochemistryNatural SciencesMedicineMechanism Of ActionChemical Biology +5

Difluoromethylene at the γ-Lactam α-Position Improves 11-Deoxy-8-aza-PGE₁ Series EP₄ Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE₁ Analog (KMN-159) as a Potent EP₄ Agonist

Stephen D. Barrett, Melissa C. Holt, James B. Kramer, +10

Journal of Medicinal Chemistry

The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones

Fred L. Ciske, Michael R. Barbachyn, Michaël Génin, +9

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBioorganic ChemistryBiochemistryNatural SciencesAntibacterial Activity +6

Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-<i>exo</i> Amide−Epoxide Cyclization

Noel A. Powell, Fred L. Ciske, Emma C. Clay, +5

Organic Letters

Practical SynthesisEngineeringRing-opening CyclizationKetopiperazine C6-n1 BondOrganic Chemistry +8

A Convenient Synthesis of Dengibsin

Winton D. Jones, Fred L. Ciske

The Journal of Organic Chemistry

Bioorganic ChemistryEngineeringChemical AnalysisAromatic CompoundsAltmetric Attention Score +14

Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Noel A. Powell, Jennifer K. Hoffman, Fred L. Ciske, +11

Bioorganic & Medicinal Chemistry Letters

MedicinePharmacological AgentPharmacotherapyAnti-cancer AgentPharmacology +2

An Efficient Synthesis of Dihydroxyfluorenones via in Situ Pd(0)-Catalyzed Cross-Coupling

Fred L. Ciske

Synthesis

Chemical EngineeringSitu PdEngineeringCross-coupling ReactionFluorous Synthesis +5