Melissa C. Holt - Concepedia

Author

Melissa C. Holt

Cayman Chemical (United States)ORCID

Also Known As

Chris Holt, Holt, Melissa C., M.C. Holt, Melissa C Holt, Melissa C. Holt, Melissa Holt, Z. Assar

Publications

406

Citations

H-Index

Concepts

All Affiliations

Cayman Chemical (United States)Virginia Commonwealth University

About

Melissa C. Holt is an author at Cayman Chemical (United States) specializing in medicine, pharmacology, and pharmacotherapy.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	225
2	Biochemistry	3	3	147
3	Health Sciences	2	2	78
4	Natural Sciences	1	1	39
5	Anesthesia	1	1	54

Melissa C. Holt

Publications

258

Citations

H-Index

Page 1

	Year	Citations
Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety Frederick Cohen, James B. Aggen, Logan D. Andrews, ChemMedChem Antibiotic AdjuvantCardiovascular PharmacologyPharmacotherapyAntimicrobial ChemotherapyPharmaceutical Chemistry	2019	75
Respiratory depressant effects of fentanyl analogs are opioid receptor-mediated Neil B. Varshneya, Sherif H. Hassanien, Melissa C. Holt, Biochemical Pharmacology Opioid EpidemicFentanylAddictionMedicineFentanyl Analogs	2021	54
Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors Melissa C. Holt, Zahra Assar, Reza Beheshti Zavareh, Biochemistry Aldo-keto ReductaseMolecular BiologyPlp SitePancreatic Cancer CellsCancer Biology	2018	39
Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors Daniel R. Goldberg, Stéphane De Lombaert, Robert J. Aiello, Bioorganic & Medicinal Chemistry Letters Spirocyclic ProlineBiochemistryMedicineRational Drug DesignPharmacotherapy	2016	33
Difluoromethylene at the γ-Lactam α-Position Improves 11-Deoxy-8-aza-PGE<sub>1</sub> Series EP<sub>4</sub> Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE<sub>1</sub> Analog (KMN-159) as a Potent EP<sub>4</sub> Agonist Stephen D. Barrett, Melissa C. Holt, James B. Kramer, Journal of Medicinal Chemistry	2019	33
Fentanyl analog structure-activity relationships demonstrate determinants of diverging potencies for antinociception and respiratory depression Neil B. Varshneya, Sherif H. Hassanien, Melissa C. Holt, Pharmacology Biochemistry and Behavior Health SciencesFunctional SelectivityPain MedicineMedicinePhysiology	2023	24

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