Neuroprotection by propargylamines in Parkinson’s disease: intracellular mechanism underlying the anti-apoptotic function and search for clinical markers

Mitochondrial Complex I Deficiency in Parkinson's Disease

Anthony H.V. Schapira, Jonathan M. Cooper, David T. Dexter et al. · Journal of Neurochemistry · 1990 · 2.3K citations

Life Sciences, Neurobiology, Neuroscience +13

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

Shigeomi Shimizu, Masashi Narita, Yoshihide Tsujimoto et al. · Nature · 1999 · 2.2K citations

Life Sciences, Biochemistry, Molecular Biology +10

Direct brain infusion of glial cell line–derived neurotrophic factor in Parkinson disease

Steven S. Gill, Nikunj K. Patel, Gary Hotton et al. · Nature Medicine · 2003 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +17

Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis

Solange Desagher, Astrid Osen‐Sand, Anthony C. Nichols et al. · The Journal of Cell Biology · 1999 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome <i>c</i> release in isolated mitochondria

Masashi Narita, Shigeomi Shimizu, Toshinori Ito et al. · Proceedings of the National Academy of Sciences · 1998 · 925 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17