W. Maruyama

In parkinsonian substantia nigra, α-synuclein is modified by acrolein, a lipid-peroxidation product, and accumulates in the dopamine neurons with inhibition of proteasome activity

Masayo Shamoto‐Nagai, W. Maruyama, Yoshio Hashizume et al. · Journal of Neural Transmission · 2007 · 113 citations

Neurodegenerative Diseases, Biochemistry, Medicine +12

Enhancing effect of rasagiline on superoxide dismutase and catalase activities in the dopaminergic system in the rat

Marı́a C. Carrillo, C. Minami, Kenichi Kitani et al. · Life Sciences · 2000 · 111 citations

Biochemistry, Medicine, Neuropharmacology +11

Aging attenuates glucocorticoid negative feedback in rat brain

Kazushige Mizoguchi, Ryuji Ikeda, Hirotaka Shoji et al. · Neuroscience · 2008 · 103 citations

Aging, Neurophysiology, Longevity +7

The anti-Parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells.

W. Maruyama, Tsutomu Takahashi, Moussa B. H. Youdim et al. · Journal of Neural Transmission · 2002 · 102 citations

Medicine, Apoptosis, Cell Death +7

Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells

Takashi Yamamoto, W. Maruyama, Yoji Kato et al. · Journal of Neural Transmission · 2002 · 102 citations

Biochemistry, Mitochondrial Function, Selective Nitration +8