2005 · 25 citations · 15 references
ComputingBioinformaticsBiologyDatabasesKnowledge RepresentationPathway AnalysisDescription LogicsFormal OntologyOntology DesignOntology EngineeringPathway CurationPathway DatabasesDescription Logic OntologiesPathway InteroperabilityPathway Knowledge RepresentationPathway OntologiesPathway Representation FormatsPathway Schema DesignSemantic WebSemantic Web Ontologies
Abstract. We report on experiences using OWL DL in the design of an exchange format for biological pathway information. Although the working group charged with this task was not initially very familiar with OWL and knew that the technology around OWL wasn't mature, they chose it because of its ability to express complex relationships in a formal and computable manner. The subsequent journey has not been smooth. Delightful discoveries about OWL have alternated with surprises about how difficult it is to operate correctly inside open world description logics and the Semantic Web generally. This paper highlights experience that may be of interest to the OWL community, including ontology developers, tool developers, and those interested in promoting the adoption of the Semantic Web. 1
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Gene Ontology: tool for the unification of biology
Michael Ashburner, Catherine A. Ball, Judith A. Blake et al. · Nature Genetics · 2000 · 44.6K citations · Full text
BIND--The Biomolecular Interaction Network Database
Gary D. Bader · Nucleic Acids Research · 2001 · 1.6K citations · Full text
Resource description framework
K. Selçuk Candan, Huan Liu, Reshma Suvarna · ACM SIGKDD Explorations Newsletter · 2001 · 1.1K citations
Relations in biomedical ontologies
Barry Smith, Werner Ceusters, Bert R. E. Klagges et al. · Genome biology · 2005 · 1K citations · Full text
Computing, Biomedical Informatics, Health Data Interoperability +14