Genetic Determinants of Methotrexate Toxicity in Tunisian Patients with Rheumatoid Arthritis: A Study of Polymorphisms Involved in the MTX Metabolic Pathway

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

Frank C. Arnett, Steven M. Edworthy, D. Blöch et al. · Arthritis & Rheumatism · 1988 · 19.9K citations

Medicine, Clinical Sciences, Internal Medicine +12

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

Josef S Smolen, Robert Landewé, Ferdinand C. Breedveld et al. · Annals of the Rheumatic Diseases · 2013 · 1.8K citations · Full text

Medicine, Internal Medicine, Pharmacotherapy +15

Efficiency and power in genetic association studies

Paul I. W. de Bakker, Roman Yelensky, Itsik Pe’er et al. · Nature Genetics · 2005 · 1.7K citations

Life Sciences, Biostatistics, Genetics +11

A Second Common Mutation in the Methylenetetrahydrofolate Reductase Gene: An Additional Risk Factor for Neural-Tube Defects?

N.M.J. van der Put, F. Gabreëls, E M Stevens et al. · The American Journal of Human Genetics · 1998 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

A fast method for high-quality genomic DNA extraction from whole human blood.

Stefano Gustincich, Guidalberto Manfioletti, Giannino Del Sal et al. · PubMed · 1991 · 606 citations

Life Sciences, Genetics, Molecular Biology +10