Concepedia

Methotrexate Nephrotoxicity

Methotrexate Nephrotoxicity is a form of drug-induced kidney injury characterized by renal dysfunction resulting from the accumulation of methotrexate, a chemotherapeutic and immunomodulatory agent, leading to tubular epithelial damage and impaired glomerular filtration.

351

Publications

15.5K

Citations

1.6K

Authors

555

Institutions

Publications per year

2017–2026

101

Parents

Publications

351

CLINICAL AND PHARMACOKINETIC EVIDENCE OF A LIFE-THREATENING INTERACTION BETWEEN METHOTREXATE AND KETOPROFEN

A. Thyss, Johanna Kubar, G. Milano et al. · The Lancet · 1986 · 252 citations

, , +10

Melatonin prevents methotrexate‐induced hepatorenal oxidative injury in rats

Nermina Jahovic, Hülya Çevik, A. Özer Şehirli et al. · Journal of Pineal Research · 2003 · 245 citations

, , +17

Consensus Guideline for Use of Glucarpidase in Patients with High-Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance

Laura B. Ramsey, Frank M. Balis, Maureen M. O’Brien et al. · The Oncologist · 2017 · 217 citations · Full text

, , +17

Concepts in use of high-dose methotrexate therapy

Steven P. Treon, Bruce A. Chabner · Clinical Chemistry · 1996 · 185 citations · Full text

, , +17

Glucarpidase, Leucovorin, and Thymidine for High-Dose Methotrexate-Induced Renal Dysfunction: Clinical and Pharmacologic Factors Affecting Outcome

Brigitte C. Widemann, Frank M. Balis, AeRang Kim et al. · Journal of Clinical Oncology · 2010 · 173 citations · Full text

, , +17

1–5 of 351

Authors

1.6K

  1. BC
    Brigitte C. Widemann

    National Cancer Institute, United States

    5 publications · 677 citations

    5

    h-index

  2. AA
    Azza A. K. El‐Sheikh

    Minia University, Egypt

    4 publications · 133 citations

    4

    h-index

  3. FM
    Frank M. Balis

    National Cancer Institute, United States

    4 publications · 586 citations

    4

    h-index

  4. AM
    Ayman M. Mahmoud

    Beni-Suef University, Egypt

    5 publications · 567 citations

    4

    h-index

  5. EH
    Emad H. M. Hassanein

    Al-Azhar University, Egypt

    4 publications · 260 citations

    4

    h-index

1–5 of 1.6K

Institutions

555

  1. Al-Azhar University

    Cairo, Egypt

    9 h-index

    27 publications

    1.2K citations

  2. Beni-Suef University

    Banī Suwayf, Egypt

    8 h-index

    21 publications

    2K citations

  3. Minia University

    Minya, Egypt

    8 h-index

    26 publications

    1.6K citations

  4. St. Jude Children's Research Hospital

    Memphis, United States

    7 h-index

    24 publications

    2.3K citations

  5. Harvard University

    Cambridge, United States

    7 h-index

    24 publications

    1.5K citations

  6. University of Alabama at Birmingham

    Birmingham, United States

    7 h-index

    26 publications

    960 citations

  7. King Faisal University

    Hofuf, Saudi Arabia

    6 h-index

    13 publications

    636 citations

  8. Assiut University

    Asyut, Egypt

    6 h-index

    8 publications

    429 citations

1–8 of 555

Venues

  1. PubMed

    Repository · 52 publications · 1.9K citations

    27

    h-index

  2. Cancer Chemotherapy and Pharmacology

    15 publications · 462 citations

    14

    h-index

  3. Leukemia & lymphoma/Leukemia and lymphoma

    8 publications · 262 citations

    8

    h-index

  4. Pediatric Blood & Cancer

    9 publications · 264 citations

    8

    h-index

  5. Renal Failure

    7 publications · 364 citations

    7

    h-index

1–5