Concepedia

Comparative Effects of the Renin–Angiotensin System Blockers on Nonalcoholic Fatty Liver Disease and Insulin Resistance in C57Bl/6 Mice

Eliete Dalla Corte Frantz, Aline Penna‐de‐Carvalho, Thais de Medeiros Batista, Márcia Barbosa Águila, Carlos Alberto Mandarim‐de‐Lacerda

Metabolic Syndrome and Related Disorders · 2014 · 23 citations · 23 references

DOI

Abstract

Enalapril was the most successful treatment in protecting against hepatic IR and NAFLD by enhancing hepatic insulin action, leptin, and gluconeogenesis and by reducing the lipogenic pathway and lipid accumulation in the liver.

References

23

AIN-93 Purified Diets for Laboratory Rodents: Final Report of the American Institute of Nutrition Ad Hoc Writing Committee on the Reformulation of the AIN-76A Rodent Diet

Philip G. Reeves, Forrest H. Nielsen, G. C. Fahey · Journal of Nutrition · 1993 · 8.6K citations

, , +12

Insulin signalling and the regulation of glucose and lipid metabolism

Alan R. Saltiel, C. Ronald Kahn · Nature · 2001 · 5.2K citations · Full text

, , +13

Nonalcoholic Steatohepatitis: A Proposal for Grading and Staging The Histological Lesions

Elizabeth M. Brunt, Christine G. Janney, Adrian M. Di Bisceglie et al. · The American Journal of Gastroenterology · 1999 · 3.8K citations

Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

R. Scott Rector, John P. Thyfault, Grace M. Uptergrove et al. · Journal of Hepatology · 2010 · 477 citations · Full text

, , +18

Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II

Ramón Bataller, Pau Sancho‐Bru, Pere Ginès et al. · Gastroenterology · 2003 · 355 citations

, , +10