Concepedia

Hepatic Gluconeogenesis

Hepatic Gluconeogenesis is a metabolic process—in the broader class of gluconeogenic pathways—defined by its exclusive occurrence in the liver, where it mediates the de novo synthesis of glucose from non-carbohydrate precursors to maintain systemic glucose homeostasis.

3.1K

Publications

195.9K

Citations

11.4K

Authors

2.1K

Institutions

Publications per year

2017–2026

419

Parents

Publications

3.1K

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

Mark R. Owen, E. Doran, Andrew P. Halestrap · Biochemical Journal · 2000 · 2.1K citations · Full text

, , +17

The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

Reuben J. Shaw, Katja Lamia, Debbie S. Vasquez et al. · Science · 2005 · 1.9K citations

, , +17

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

John C. Yoon, Pere Puigserver, Guoxun Chen et al. · Nature · 2001 · 1.8K citations

, , +14

Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction

Pere Puigserver, James Rhee, Jerry Donovan et al. · Nature · 2003 · 1.5K citations

, , +14

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

Stephan Herzig, Fanxin Long, Ulupi S. Jhala et al. · Nature · 2001 · 1.4K citations

, , +13

1–5 of 3.1K

Authors

11.4K

  1. AD
    Alan D. Cherrington

    Vanderbilt University, United States

    76 publications · 5.2K citations

    37

    h-index

  2. GI
    Gerald I. Shulman

    Yale University, United States

    35 publications · 7.3K citations

    29

    h-index

  3. DW
    Doss W. Neal

    Vanderbilt University, United States

    37 publications · 1.8K citations

    25

    h-index

  4. BR
    Bernard R. Landau

    Case Western Reserve University, United States

    25 publications · 1.7K citations

    22

    h-index

  5. JH
    John H. Exton

    Vanderbilt University, United States

    21 publications · 3.7K citations

    21

    h-index

1–5 of 11.4K

Institutions

2.1K

  1. Vanderbilt University

    Nashville, United States

    61 h-index

    600 publications

    50.4K citations

  2. Harvard University

    Cambridge, United States

    45 h-index

    295 publications

    80.6K citations

  3. The University of Texas Southwestern Medical Center

    Dallas, United States

    38 h-index

    240 publications

    32.3K citations

  4. Yale University

    New Haven, United States

    35 h-index

    262 publications

    46.2K citations

  5. Inserm

    Paris, France

    34 h-index

    244 publications

    13.1K citations

  6. Case Western Reserve University

    Cleveland, United States

    32 h-index

    185 publications

    10.3K citations

  7. University of Pennsylvania

    Philadelphia, United States

    31 h-index

    162 publications

    18.9K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    28 h-index

    93 publications

    13.6K citations

1–8 of 2.1K

Venues

  1. Journal of Biological Chemistry

    JBC · 268 publications · 28.1K citations

    96

    h-index

  2. Diabetes

    209 publications · 18.2K citations

    75

    h-index

  3. 50

    h-index

  4. Journal of Clinical Investigation

    JCI · 63 publications · 10.5K citations

    50

    h-index

  5. Biochemical Journal

    BJ · 103 publications · 7.4K citations

    43

    h-index

1–5