Concepedia

Analysis and purification of IgG4 bispecific antibodies by a mixed-mode chromatography

Xiaoyu Yang, Ying Zhang, Fengqiang Wang, Larry Wang, Daisy Richardson, Mohammed Shameem, Alexandre Ambrogelly

Analytical Biochemistry · 2015 · 33 citations · 17 references

DOI

Concepts

References

17

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Marijn van der Neut Kolfschoten, Janine Schuurman, Mario Losen et al. · Science · 2007 · 975 citations

, , +17

Marketed therapeutic antibodies compendium

Janice M. Reichert · mAbs · 2012 · 367 citations · Full text

, , +17

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange

Aran F. Labrijn, Joyce Meesters, Bart E.C.G. de Goeij et al. · Proceedings of the National Academy of Sciences · 2013 · 330 citations · Full text

, , +17

Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

Aran F. Labrijn, Antonio Ortiz Buijsse, Ewald T.J. van den Bremer et al. · Nature Biotechnology · 2009 · 290 citations

, , +10

Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms

Jette Wypych, Ming Li, Amy Guo et al. · Journal of Biological Chemistry · 2008 · 282 citations · Full text

, , +15