Janine Schuurman

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Marijn van der Neut Kolfschoten, Janine Schuurman, Mario Losen et al. · Science · 2007 · 975 citations

Life Sciences, Biochemistry, Immunology +17

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

Christoph A. Diebolder, Frank J. Beurskens, Rob N. de Jong et al. · Science · 2014 · 784 citations

Life Sciences, Immunology, Molecular Biology +14

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange

Aran F. Labrijn, Joyce Meesters, Bart E.C.G. de Goeij et al. · Proceedings of the National Academy of Sciences · 2013 · 330 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +17

Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

Aran F. Labrijn, Antonio Ortiz Buijsse, Ewald T.J. van den Bremer et al. · Nature Biotechnology · 2009 · 290 citations

Life Sciences, Biochemistry, Molecular Biology +10

A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor–Resistant Lung Tumors

Sheri L. Moores, Mark L. Chiu, Barbara S. Bushey et al. · Cancer Research · 2016 · 283 citations

Medicine, Oncology, Pharmacology +17