Janine Schuurman

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Marijn van der Neut Kolfschoten, Janine Schuurman, Mario Losen et al. · Science · 2007 · 957 citations

Human Igg4 Antibodies, Innate Immune System, Immunology +20

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

Christoph A. Diebolder, Frank J. Beurskens, Rob N. de Jong et al. · Science · 2014 · 764 citations

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange

Aran F. Labrijn, Joyce Meesters, Bart E.C.G. de Goeij et al. · Proceedings of the National Academy of Sciences · 2013 · 322 citations · Full text

Engineering, Immunology, Molecular Biology +22

Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

Aran F. Labrijn, Antonio Ortiz Buijsse, Ewald T.J. van den Bremer et al. · Nature Biotechnology · 2009 · 286 citations

Autoimmune Disease, Therapeutic Igg4 Antibodies, Immunology +12

Targeting interleukin‐15 in patients with rheumatoid arthritis: A proof‐of‐concept study

Bo Baslund, N. Tvede, Bente Danneskiold‐Samsøe et al. · Arthritis & Rheumatism · 2005 · 263 citations