Aran F. Labrijn

Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41

Michael B. Zwick, Aran F. Labrijn, Meng Wang et al. · Journal of Virology · 2001 · 780 citations · Full text

Access of Antibody Molecules to the Conserved Coreceptor Binding Site on Glycoprotein gp120 Is Sterically Restricted on Primary Human Immunodeficiency Virus Type 1

Aran F. Labrijn, Pascal Poignard, Aarti Raja et al. · Journal of Virology · 2003 · 353 citations · Full text

Immunology, Glycobiology, Molecular Biology +18

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange

Aran F. Labrijn, Joyce Meesters, Bart E.C.G. de Goeij et al. · Proceedings of the National Academy of Sciences · 2013 · 322 citations · Full text

Engineering, Immunology, Molecular Biology +22

Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

Aran F. Labrijn, Antonio Ortiz Buijsse, Ewald T.J. van den Bremer et al. · Nature Biotechnology · 2009 · 286 citations

Autoimmune Disease, Therapeutic Igg4 Antibodies, Immunology +12

Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120–CD4–CCR5 complexes

Maxime Moulard, Sanjay Phogat, Yuuei Shu et al. · Proceedings of the National Academy of Sciences · 2002 · 206 citations · Full text

Immunology, Immunodominance, Molecular Biology +20