Concepedia

Engineering mammalian cell factories with SINEUP noncoding RNAs to improve translation of secreted proteins

Laura Patrucco, Andrea Della Chiesa, Maria Felicia Soluri, Francesca Fasolo, Hazuki Takahashi, Piero Carninci, S. Zucchelli, Claudio Santoro, Stefano Gustincich, Daniele Sblattero,

Gene · 2015 · 41 citations · 15 references

DOI

Concepts

References

15

Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat

Claudia Carrieri, Laura Cimatti, Marta Biagioli et al. · Nature · 2012 · 1K citations · Full text

, , +15

The elastin gene is disrupted by a translocation associated with supravalvular aortic stenosis

Michael A. Curran · Cell · 1993 · 423 citations

, , +13

Advances in Mammalian Cell Line Development Technologies for Recombinant Protein Production

Tingfeng Lai, Yuansheng Yang, Say Kong Ng · Pharmaceuticals · 2013 · 322 citations · Full text

, , +17

A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies

Minsoo Kim, Peter M. O’Callaghan, Kurt A. Droms et al. · Biotechnology and Bioengineering · 2011 · 212 citations

, , +17

High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells

Volker Jäger, Konrad Büssow, Andreas Wagner et al. · BMC Biotechnology · 2013 · 201 citations · Full text

, , +17