Isolation and characterization of human cathepsin V: a major proteinase in corneal epithelium.

Wakako Adachi, Shoko Kawamoto, I. Ohno, Keigo Nishida, Shigeru Kinoshita, K Matsubara, Kousaku Okubo

PubMed · 1998 · 77 citations · 0 references

Abstract

The amino acid homology and proteolytic activity of the recombinant protein indicate that the novel gene is a new member of the cathepsins that have features of cysteine proteinase. Its uniquely high expression in corneal epithelium strongly implies an important role in corneal physiology.