Engineering dispersed mycelium morphology in Aspergillus niger for enhanced mycoprotein production via CRISPR/Cas9-mediated genome editing

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders · Genome biology · 2014 · 100.5K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +15

HISAT: a fast spliced aligner with low memory requirements

Daehwan Kim, Ben Langmead, Steven L. Salzberg · Nature Methods · 2015 · 26.1K citations · Full text

Engineering, Computer Engineering, Computer Science +3

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

Mihaela Pertea, Geo Pertea, Corina Antonescu et al. · Nature Biotechnology · 2015 · 15.5K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +10

A genomic approach for the identification and classification of genes involved in cell wall formation and its regulation in <i>Saccharomyces cerevisiae</i>

Piet W. J. de Groot, Cristina Ruíz‐Romero, Carlos R. Vázquez de Aldana et al. · Comparative and Functional Genomics · 2001 · 162 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

5S rRNA Promoter for Guide RNA Expression Enabled Highly Efficient CRISPR/Cas9 Genome Editing in <i>Aspergillus niger</i>

Xiaomei Zheng, Ping Zheng, Kun Zhang et al. · ACS Synthetic Biology · 2018 · 160 citations

Life Sciences, Biotechnology, Molecular Biology +16