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Short-Chain Fatty Acid Aggregates Alpha-Synuclein Accumulation and Neuroinflammation via GPR43-NLRP3 Signaling Pathway in a Model Parkinson’s Disease

Yi Qu, Ke An, Danlei Wang, Jingyi Li, Zhe Min, Yongjie Xiong, Zheng Xue, Zhijuan Mao

Molecular Neurobiology · 2025 · 23 citations · 33 references

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33

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

Timothy R. Sampson, Justine W. Debelius, Taren Thron et al. · Cell · 2016 · 3.6K citations · Full text

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Host microbiota constantly control maturation and function of microglia in the CNS

Daniel Erny, Anna Lena Hrabě de Angelis, Diego Adhemar Jaitin et al. · Nature Neuroscience · 2015 · 3.4K citations · Full text

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Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

Nagendra Singh, Ashish Gurav, Sathish Sivaprakasam et al. · Immunity · 2014 · 2.3K citations · Full text

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Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

Sangjune Kim, Seung‐Hwan Kwon, Tae‐In Kam et al. · Neuron · 2019 · 1.4K citations · Full text

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Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls

Marcus M. Unger, Jörg Spiegel, Klaus-Ulrich Dillmann et al. · Parkinsonism & Related Disorders · 2016 · 1.2K citations

, , +16