A novel biosensor for detecting V. parahaemolyticus based on cascade signal amplification of CRISPR/Cas14a and Exo III

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

Lucas B. Harrington, David Burstein, Janice S. Chen et al. · Science · 2018 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Massively multiplexed nucleic acid detection with Cas13

Cheri M. Ackerman, Cameron Myhrvold, Sri Gowtham Thakku et al. · Nature · 2020 · 809 citations · Full text

Medicine, Microbiology, Molecular Biology +17

Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2

Jon Arizti-Sanz, Catherine A. Freije, Alexandra C. Stanton et al. · Nature Communications · 2020 · 518 citations · Full text

Medicine, Infectious Diseases, Microbiology +17

An ultrasensitive CRISPR/Cas12a based electrochemical biosensor for Listeria monocytogenes detection

Fan Li, Qinghua Ye, Moutong Chen et al. · Biosensors and Bioelectronics · 2021 · 289 citations

Life Sciences, Biotechnology, Microbiology +16

RPA-Cas12a-FS: A frontline nucleic acid rapid detection system for food safety based on CRISPR-Cas12a combined with recombinase polymerase amplification

Hua Liu, Jinbin Wang, Haijuan Zeng et al. · Food Chemistry · 2020 · 190 citations

Life Sciences, Biotechnology, Genetics +14