Concepedia

A CAR enhancer increases the activity and persistence of CAR T cells

Taha Rakhshandehroo, Shreya R. Mantri, Seyed Heydar Moravej, Benjamin B. V. Louis, Ali Salehi Farid, Leila Munaretto, Kathryn Regan, Radia M. M. Khan, A Wolff, Zoe Farkash,

Nature Biotechnology · 2024 · 41 citations · 34 references

DOIFull text

Open access

Concepts

References

34

CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

Cameron J. Turtle, Laïla‐Aïcha Hanafi, Carolina Berger et al. · Journal of Clinical Investigation · 2016 · 2.1K citations · Full text

, , +17

Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma

Noopur Raje, Jesús G. Berdeja, Yi Lin et al. · New England Journal of Medicine · 2019 · 1.7K citations · Full text

, , +17

Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition

Leonid Cherkassky, Aurore Morello, Jonathan Villena‐Vargas et al. · Journal of Clinical Investigation · 2016 · 1.1K citations · Full text

, , +17

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

Joseph A. Fraietta, Christopher L. Nobles, Morgan A. Sammons et al. · Nature · 2018 · 861 citations · Full text

, , +14

B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma

Adam D. Cohen, Alfred L. Garfall, Edward A. Stadtmauer et al. · Journal of Clinical Investigation · 2019 · 790 citations · Full text

, , +17