Concepedia

Physicochemical and structural insights into lyophilized mRNA-LNP from lyoprotectant and buffer screenings

Yuchen Fan, Diamanda Rigas, Lee Joon Kim, Feng-Peng Chang, Nanzhi Zang, K C McKee, C. Kemball, Zhixin Yu, P. Winkler, Wan-Chih Su,

Journal of Controlled Release · 2024 · 58 citations · 50 references

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References

50

Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles

Marianna Yanez Arteta, Tomas Kjellman, Stefano Bartesaghi et al. · Proceedings of the National Academy of Sciences · 2018 · 525 citations · Full text

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IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines

Siri Tähtinen, Ann-Jay Tong, Patricia Himmels et al. · Nature Immunology · 2022 · 519 citations · Full text

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Endosomal escape: A bottleneck for LNP-mediated therapeutics

Sushmita Chatterjee, Edo Kon, Preeti Sharma · Proceedings of the National Academy of Sciences · 2024 · 474 citations · Full text

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Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration

Manuel Carrasco, Suman Alishetty, Mohamad‐Gabriel Alameh et al. · Communications Biology · 2021 · 408 citations · Full text

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Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques

Frank Liang, Gustaf Lindgren, Ang Lin et al. · Molecular Therapy · 2017 · 400 citations · Full text

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