Concepedia

Probiotics induce intestinal IgA secretion in weanling mice potentially through promoting intestinal APRIL expression and modulating the gut microbiota composition

Maozhen Zhao, Xi Liang, Meng Yang, Haiyan Lü, Kai Lin, Pimin Gong, Tongjie Liu, Huaxi Yi, Jiancun Pan, Yongjiu Zhang,

Food & Function · 2024 · 18 citations · 49 references

DOI

Concepts

Abstract

FL276.1 can induce IgA production in the intestinal tract of weanling mice by promoting intestinal APRIL expression and mediating changes in the gut microbiota, thus playing a significant role in enhancing local intestinal immunity in infants.

References

49

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Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRIL

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A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the Adult

Ziad Al Nabhani, Sophie Dulauroy, Rute Marques et al. · Immunity · 2019 · 667 citations · Full text

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