Dietary tryptophan improves growth and intestinal health by promoting the secretion of intestinal β-defensins against enterotoxigenic Escherichia coli F4 in weaned piglets

Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptor

Samantha A. Scott, Jingjing Fu, Pamela V. Chang · Proceedings of the National Academy of Sciences · 2020 · 621 citations · Full text

Life Sciences, Immunology, Microbiology +17

Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice

Seung‐Chul Choi, Josephine Brown, Minghao Gong et al. · Science Translational Medicine · 2020 · 261 citations · Full text

Life Sciences, Immunology, Microbiology +16

Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1

Zhifa Wen, Hongxiang Liu, Rong Gao et al. · Journal for ImmunoTherapy of Cancer · 2018 · 171 citations · Full text

Medicine, Immunology, Oncology +17

Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota

David M. Alvarado, Baosheng Chen, Micah Iticovici et al. · Gastroenterology · 2019 · 153 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Physiological roles of tryptophan in teleosts: current knowledge and perspectives for future studies

Seyyed Morteza Hoseini, Amalia Pérez‐Jiménez, Benjamín Costas et al. · Reviews in Aquaculture · 2017 · 141 citations · Full text

Life Sciences, Biochemistry, Physiology +17