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Senolytic treatment fails to improve ovarian reserve or fertility in female mice

Driele N. Garcia, Jéssica D. Hense, Bianka M. Zanini, José V.V. Isola, Juliane B. Prosczek, Sarah Ashiqueali, Thaís Larré Oliveira, Jeffrey B. Mason, Ines Schadock, Carlos Castilho Barros,

GeroScience · 2024 · 17 citations · 23 references

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23

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Yi Zhu, Tamar Tchkonia, Tamar Pirtskhalava et al. · Aging Cell · 2015 · 2.4K citations · Full text

, , +17

Senolytics improve physical function and increase lifespan in old age

Ming Xu, Tamar Pirtskhalava, Joshua N. Farr et al. · Nature Medicine · 2018 · 2.2K citations

, , +14

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

LaTonya J. Hickson, Larissa Prata, Shane A. Bobart et al. · EBioMedicine · 2019 · 1.3K citations · Full text

, , +17

Fisetin is a senotherapeutic that extends health and lifespan

Matthew J. Yousefzadeh, Yi Zhu, Sara J. McGowan et al. · EBioMedicine · 2018 · 978 citations · Full text

, , +17

Methods for quantifying follicular numbers within the mouse ovary

Mark A. Myers, Kara L. Britt, Nigel G. Wreford et al. · Reproduction · 2004 · 771 citations · Full text

, , +17