Sara J. McGowan

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Yi Zhu, Tamar Tchkonia, Tamar Pirtskhalava et al. · Aging Cell · 2015 · 2.3K citations · Full text

Apoptosis, Immunology, Immune Regulation +18

Fisetin is a senotherapeutic that extends health and lifespan

Matthew J. Yousefzadeh, Yi Zhu, Sara J. McGowan et al. · EBioMedicine · 2018 · 913 citations · Full text

An aged immune system drives senescence and ageing of solid organs

Matthew J. Yousefzadeh, Rafael R. Flores, Yi Zhu et al. · Nature · 2021 · 881 citations · Full text

Inflammation, Autoimmune Disease, Anti-aging +11

Identification of HSP90 inhibitors as a novel class of senolytics

Heike Fuhrmann‐Stroissnigg, Yuan Yuan Ling, Jing Zhao et al. · Nature Communications · 2017 · 651 citations · Full text

Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice

Matthew J. Yousefzadeh, Jing Zhao, Christina Bukata et al. · Aging Cell · 2020 · 300 citations · Full text