Heike Fuhrmann‐Stroissnigg

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Yi Zhu, Tamar Tchkonia, Tamar Pirtskhalava et al. · Aging Cell · 2015 · 2.3K citations · Full text

Apoptosis, Immunology, Immune Regulation +18

Cellular senescence mediates fibrotic pulmonary disease

Marissa J. Schafer, Thomas A. White, Koji Iijima et al. · Nature Communications · 2017 · 1.5K citations · Full text

Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors

Yi Zhu, Tamar Tchkonia, Heike Fuhrmann‐Stroissnigg et al. · Aging Cell · 2015 · 1.1K citations · Full text

Apoptosis, Immunology, Cell Death +17

Fisetin is a senotherapeutic that extends health and lifespan

Matthew J. Yousefzadeh, Yi Zhu, Sara J. McGowan et al. · EBioMedicine · 2018 · 913 citations · Full text

New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463

Yi Zhu, Ewald J. Doornebal, Tamar Pirtskhalava et al. · Aging · 2017 · 687 citations · Full text