Oxidative stress-activated Nrf2 remitted polystyrene nanoplastic-induced mitochondrial damage and inflammatory response in HepG2 cells

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Masaaki Komatsu, Satoshi Waguri, Keiko Taguchi et al. · Nature Cell Biology · 2010 · 2.4K citations

Life Sciences, Cell Biology, Molecular Biology +14

Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Xiaofang Sun, Zhanhui Ou, Ruochan Chen et al. · Hepatology · 2015 · 2K citations · Full text

Life Sciences, Cell Biology, Oncology +17

Characterisation, quantity and sorptive properties of microplastics extracted from cosmetics

Imogen E. Napper, Adil Bakir, Steven J. Rowland et al. · Marine Pollution Bulletin · 2015 · 956 citations · Full text

Natural Sciences, Chemical Engineering, Chemistry +7

Microplastics detected in cirrhotic liver tissue

Thomas Horvatits, Matthias Tamminga, Beibei Liu et al. · EBioMedicine · 2022 · 691 citations · Full text

Medicine, Pathology, Toxicology +17

Internalization and toxicity: A preliminary study of effects of nanoplastic particles on human lung epithelial cell

Mingkai Xu, Gulinare Halimu, Qianru Zhang et al. · The Science of The Total Environment · 2019 · 644 citations

Life Sciences, Cell Biology, Toxicology +15