Annals of Medicine and Surgery · 2024 · 40 citations · 36 references
The gut microbiota is emerging as a potential therapeutic target for CVD prevention and management. However, current research has limitations, including the need for larger and more diverse studies, the challenges of establishing causality, and concerns regarding the long-term consequences and safety of gut microbiota modulation. Despite these limitations, understanding the gut-heart axis holds promise for the development of personalized therapies and interventions for cardiovascular health. Further research is needed to expand our knowledge and address the ethical and safety issues associated with gut microbiota modification.
36
A human gut microbial gene catalogue established by metagenomic sequencing
Junjie Qin, Ruiqiang Li, Jeroen Raes et al. · Nature · 2010 · 11.4K citations · Full text
Diversity of the Human Intestinal Microbial Flora
Paul B. Eckburg, Elisabeth M. Bik, Çharles N. Bernstein et al. · Science · 2005 · 7.7K citations · Full text
Metagenomic Analysis of the Human Distal Gut Microbiome
Steven R. Gill, Mihai Pop, Robert T. DeBoy et al. · Science · 2006 · 4.6K citations · Full text
Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk
W.H. Wilson Tang, Zeneng Wang, Bruce S. Levison et al. · New England Journal of Medicine · 2013 · 3.2K citations · Full text