Concepedia

Discovery of a PROTAC degrader for METTL3-METTL14 complex

Wenhao Du, Yuting Huang, Xiaoai Chen, Yue Deng, Yaoliang Sun, Hong Yang, Qiongyu Shi, Feifei Wu, Guobin Liu, He Huang,

Cell chemical biology · 2024 · 63 citations · 22 references

DOI

Concepts

References

22

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

Shuibin Lin, Junho Choe, Peng Du et al. · Molecular Cell · 2016 · 1.6K citations · Full text

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m <sup>6</sup> A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

Shay Geula, Sharon Moshitch-Moshkovitz, Dan Dominissini et al. · Science · 2015 · 1.6K citations · Full text

, , +17

RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2

Mengnuo Chen, Lai Wei, Cheuk‐Ting Law et al. · Hepatology · 2017 · 1.5K citations

, , +17

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Eliza Yankova, Wesley Blackaby, Mark R. Albertella et al. · Nature · 2021 · 1.3K citations · Full text

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The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

Ly Vu, Brian F. Pickering, Yuanming Cheng et al. · Nature Medicine · 2017 · 1.3K citations · Full text

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