SIRT1 activated by AROS sensitizes glioma cells to ferroptosis via induction of NAD+ depletion-dependent activation of ATF3

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 17K citations · Full text

Iron Deficiency, Nonapoptotic Cell Death, Metalloprotein +9

Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.1K citations · Full text

Tumor Biology, Medicine, Apoptosis +5

Glutaminolysis and Transferrin Regulate Ferroptosis

Minghui Gao, Prashant Monian, Nosirudeen Quadri et al. · Molecular Cell · 2015 · 1.9K citations · Full text

Biochemistry, Natural Sciences, Heme Signaling +6

ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation

Eunhee Park, Su Wol Chung · Cell Death and Disease · 2019 · 849 citations · Full text

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc–

Liyuan Wang, Yichen Liu, Tingting Du et al. · Cell Death and Differentiation · 2019 · 776 citations · Full text