Autophagy of OTUD5 destabilizes GPX4 to confer ferroptosis-dependent kidney injury

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

José Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth et al. · Nature Cell Biology · 2014 · 3.5K citations

Glomerulonephritis, Urology, Renal Function +12

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

Weimin Wang, Michael D. Green, Jae Eun Choi et al. · Nature · 2019 · 2.7K citations · Full text

Cancer Immunosurveillance, Immunology, Tumor Immunity +7

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

James Brugarolas, Kui Lei, Rebecca L. Hurley et al. · Genes & Development · 2004 · 1.4K citations · Full text

Synchronized renal tubular cell death involves ferroptosis

Andreas Linkermann, Rachid Skouta, Nina Himmerkus et al. · Proceedings of the National Academy of Sciences · 2014 · 1.1K citations · Full text

A Deubiquitinase That Regulates Type I Interferon Production

Nobuhiko Kayagaki, Qui Phung, Salina Chan et al. · Science · 2007 · 448 citations