Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht, +9

Cell

Iron DeficiencyNonapoptotic Cell DeathMetalloproteinApoptosisPathology +7

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina, +18

Nature Chemical Biology

Proteinlipid InteractionBiochemistryNatural SciencesFerroptosis SensitivityLipid Movement +2

The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression

Guang Lei, Yilei Zhang, Pranavi Koppula, +8

Cell Research

Tumor SuppressionApoptosisRadiation ExposureRadiation EffectCell Death +9

Synchronized renal tubular cell death involves ferroptosis

Andreas Linkermann, Rachid Skouta, Nina Himmerkus, +20

Proceedings of the National Academy of Sciences

Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

Li Yang, Dongcheng Feng, Zhanyu Wang, +8

Cell Death and Differentiation

Intestinal Ischemia/reperfusionLipid PeroxidationImmunologyPathologyRedox Biology +20

Salinomycin kills cancer stem cells by sequestering iron in lysosomes

Trang Thi, Ahmed Hamaï, Antje Hienzsch, +14

Nature Chemistry

Malignant DiseaseMedicineStem Cell ToxicologyStem Cell ResearchCancer Biology +8

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

Diego Martín‐Sánchez, Olga Ruiz‐Andrés, Jonay Poveda, +8

Journal of the American Society of Nephrology

Iron MetabolismLipid PeroxidationRenal PathologyApoptosisImmunology +17

Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11

Xinbo Wang, Yueqing Chen, Xudong Wang, +14

Cancer Research

Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade

Claire Conche, Fabian Finkelmeier, Marina Pešić, +15

Gut

KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway

Wenwen Du, Jianjie Zhu, Yuanyuan Zeng, +8

Cell Death and Differentiation