Concepedia

N6-methyladenosine modification of TSC1 mRNA contributes to macrophage polarization regulated by Coptisine in DSS-induced ulcerative colitis

Min Zhao, Peiyi Li, Dan Qiao, Siyi Hua, Qiyu Yue, Yuxin Dai, Yuqiu Huang, Jiaxin Jiang, Huiting Yin, Meng Li,

Phytomedicine · 2023 · 27 citations · 27 references

DOI

Concepts

References

27

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

Jianzhao Liu, Yanan Yue, Dali Han et al. · Nature Chemical Biology · 2013 · 3.5K citations · Full text

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Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

Andrew R. Tee, Diane C. Fingar, Brendan D. Manning et al. · Proceedings of the National Academy of Sciences · 2002 · 828 citations · Full text

, , +17

The TSC-mTOR pathway regulates macrophage polarization

Vanessa Byles, Anthony J. Covarrubias, Issam Ben‐Sahra et al. · Nature Communications · 2013 · 627 citations · Full text

, , +9

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in <i>Pten</i> <sup>+/−</sup> mice

Katrina Podsypanina, Richard Lee, Chris Politis et al. · Proceedings of the National Academy of Sciences · 2001 · 571 citations · Full text

, , +17

RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming

Huilong Yin, Xiang Zhang, Pengyuan Yang et al. · Nature Communications · 2021 · 416 citations · Full text

, , +17