NBEAL2 deficiency in humans leads to low CTLA-4 expression in activated conventional T cells

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 54.5K citations · Full text

Genetics, Genomics, Gene Recognition +23

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

Damian Szklarczyk, Annika L. Gable, David Lyon et al. · Nucleic Acids Research · 2018 · 18.4K citations · Full text

Genetics, Molecular Biology, Genomics +23

The Molecular Signatures Database Hallmark Gene Set Collection

Arthur Liberzon, Chet Birger, Helga Thorvaldsdóttir et al. · Cell Systems · 2015 · 13.5K citations · Full text

Functional Genomics, Engineering, Bioinformatics Database +9

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

Maxim V. Kuleshov, Matthew R. Jones, Andrew D. Rouillard et al. · Nucleic Acids Research · 2016 · 11.1K citations · Full text

Genetics, Molecular Biology, Curated Gene Sets +20

Gene Set Knowledge Discovery with Enrichr

Zhuorui Xie, Allison Bailey, Maxim V. Kuleshov et al. · Current Protocols · 2021 · 3.5K citations · Full text

Enrichr Button, Engineering, Genetics +26