Choline and trimethylamine N-oxide impair metabolic activation of and platelet response to clopidogrel through activation of the NOX/ROS/Nrf2/CES1 pathway

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Zeneng Wang, Elizabeth Klipfell, Brian J. Bennett et al. · Nature · 2011 · 5.6K citations

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Deepak L. Bhatt, Keith A.A. Fox, Werner Hacke et al. · New England Journal of Medicine · 2006 · 2.8K citations · Full text

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Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

Weifei Zhu, Jill C. Gregory, Elin Org et al. · Cell · 2016 · 1.9K citations · Full text

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2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease

Glenn N. Levine, Eric Bates, John A. Bittl et al. · Journal of the American College of Cardiology · 2016 · 1.6K citations

Medicine, Cardiology, Internal Medicine +16

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

Zeneng Wang, Adam Roberts, Jennifer A. Buffa et al. · Cell · 2015 · 1.3K citations · Full text

Life Sciences, Microbiology, Pharmacology +13