Concepedia

Empagliflozin attenuates the renal tubular ferroptosis in diabetic kidney disease through AMPK/NRF2 pathway

QianYu Lu, LiJiao Yang, Jing‐Jie Xiao, Qing Liu, Lihua Ni, Junwei Hu, Hong Yu, Xiaoyan Wu, Baifang Zhang

Free Radical Biology and Medicine · 2022 · 192 citations · 43 references

DOI

Concepts

References

43

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

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Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy

Barry M. Brenner, Mark E. Cooper, Dick de Zeeuw et al. · New England Journal of Medicine · 2001 · 7.5K citations · Full text

, , +17

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina et al. · Nature Chemical Biology · 2016 · 4.1K citations · Full text

, , +14

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Valerian E. Kagan, Gaowei Mao, Feng Qu et al. · Nature Chemical Biology · 2016 · 2.8K citations · Full text

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Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

Scott J. Dixon, Darpan N. Patel, Matthew Welsch et al. · eLife · 2014 · 2.1K citations · Full text

, , +13