Concepedia

Publication | Closed Access

Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti–PD-1 Immunotherapy in Fibrotic Tumors

DOI

79

Citations

45

References

2022

Year

Takahiko Akiyama, Tadahito Yasuda, Tomoyuki Uchihara, Noriko Yasuda‐Yoshihara, Benjy J.Y. Tan, Atsuko Yonemura, Takashi Semba, Juntaro Yamasaki, Yoshihiro Komohara, Koji Ohnishi,
Cancer Research

Abstract

Stromal targeting with PDGFRα/β dual blockade reverses the immunosuppressive microenvironment and enhances the efficacy of immune checkpoint inhibitors in fibrotic cancer. See related commentary by Tauriello, p. 655.

References

YearCitations

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